In case the news that future Hall of Fame quarterback Peyton Manning will be out for at least two or three months wasn't enough of a deterrent, consider that WR Austin Collie is listed questionable for Indy's regular season opener against the Houston Texans. Collie is battling a foot injury and couldn't avoid the questionable tag despite practicing all this week.

Fantasy Analysis:

Considering he's been able to practice so much, consider Collie more "probable" than "questionable." That said, using Collie in your lineups this week is a gamble. The Colts offense will take a whole new form with Kerry Collins under center. Guys like Reggie Wayne and Dallas Clark have to remain starters but Pierre Garcon and Collie owners have something to be worried about. This offense may not be able to sustain the fantasy success Garcon and Collie have experienced in the last couple season. Use Collie at your own risk.